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Article

VPS-22/SNF8 regulates longevity via modulating the activity of DAF-16 in C. elegans.

Biochemical and biophysical research communications - 29 Oct 2020

Han Shanshan, Lv Yuexia, Wang Jiuxiang, Gao Meng, Yuan Fating, Wang Decheng

Abstract excerpt

Aging is regulated by complex signaling networks, the details of which remain poorly understood. Here, we demonstrate that VPS-22/SNF8, a component of endosomal sorting complex required for transport-II (ESCRT-II), regulates the lifespan of C. elegans. In this study we show that worms with vps-22/snf8 gene knockdown had a shorter lifespan than wild-type worms. The expression pattern of VPS-22/SNF8 in C. elegans...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32829877
DOI: 10.1016/j.bbrc.2020.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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