Article
The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans.
Development (Cambridge, England) - 1 May 2011
Huang Xinxin, Zhang Hui, Zhang Hong
Abstract excerpt
Like other biological processes, aging is regulated by genetic pathways. However, it remains largely unknown whether aging is determined by an innate programmed timing mechanism and, if so, how this timer is linked to the mechanisms that control developmental timing. Here, we demonstrate that sea-2, which encodes a zinc-finger protein, controls developmental timing in C. elegans larvae by regulating expression of...
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