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Article

Lysosome biogenesis mediated by vps-18 affects apoptotic cell degradation in Caenorhabditis elegans.

Molecular biology of the cell - 1 Jan 2009

Xiao Hui, Chen Didi, Fang Zhou, Xu Jing, Sun Xiaojuan, Song Song, Liu Jiajia, Yang Chonglin

Abstract excerpt

Appropriate clearance of apoptotic cells (cell corpses) is an important step of programmed cell death. Although genetic and biochemical studies have identified several genes that regulate the engulfment of cell corpses, how these are degraded after being internalized in engulfing cell remains elusive. Here, we show that VPS-18, the Caenorhabditis elegans homologue of yeast Vps18p, is critical to cell corpse...

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Identifiers

PMID: 18923146
DOI: 10.1091/mbc.e08-04-0441
PMCID: PMC2613118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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