Article
An RGS-containing sorting nexin controls Drosophila lifespan.
PloS one - 14 May 2008
Suh Jae Myoung, Stenesen Drew, Peters John M, Inoue Akiko, Cade Angela, Graff Jonathan M
Abstract excerpt
The pursuit of eternal youth has existed for centuries and recent data indicate that fat-storing tissues control lifespan. In a D. melanogaster fat body insertional mutagenic enhancer trap screen designed to isolate genes that control longevity, we identified a regulator of G protein signaling (RGS) domain containing sorting nexin, termed snazarus (sorting nexin lazarus, snz). Flies with insertions into the 5'...
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