Article

Vps54 regulates lifespan and locomotor behavior in adult <i>Drosophila melanogaster</i>

2021-08-20

Abstract excerpt

<h4>ABSTRACT</h4> Vps54 is an integral subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans -Golgi network (TGN). A destabilizing missense mutation in Vps54 causes the age-progressive motor neuron (MN) degeneration, muscle weakness, and muscle atrophy observed in the wobbler mouse, an established animal model for human MN diseas...

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Identifiers and source

Literature Corpus work: 65598a72-ca69-54af-8eab-cf406ebb1f36
DOI: 10.1101/2021.08.20.457133

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