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Article

Longitudinal white matter and cognitive development in pediatric carriers of the apolipoprotein ε4 allele.

NeuroImage - 15 Nov 2020

Remer Justin, Dean Douglas C, Chen Kewei, Reiman Rebecca A, Huentelman Matthew J, Reiman Eric M, Deoni Sean C L

Abstract excerpt

We have previously demonstrated cross-sectional differences in magnetic resonance imaging (MRI) measurements of white matter myelin and gray matter in infants with or without the apolipoprotein ε4 allele, a major genetic risk factor for late-onset Alzheimer's disease (AD). In this study, we sought to compare longitudinal MRI white matter myelin and cognitive-behavioral changes in infants and young children with...

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Identifiers

PMID: 32822813
DOI: 10.1016/j.neuroimage.2020.117243
PMCID: PMC7779366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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