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Article

Genetic risk for Alzheimer disease in children: Evidence from early-life IQ and brain white-matter microstructure.

Genes, brain, and behavior - 1 Jul 2020

Vinueza-Veloz María Fernanda, Martín-Román Carlos, Robalino-Valdivieso María Paulina, White Tonya, Kushner Steven A, De Zeeuw Chris I

Abstract excerpt

It remains unclear whether the genetic risk for late-onset Alzheimer disease (AD) is linked to premorbid individual differences in general cognitive ability and brain structure. The objective of the present study was to determine whether the genetic risk of late-onset AD is related to premorbid individual differences in intelligence quotient (IQ) and characteristics of the cerebral white-matter in children. The...

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PMID: 32383552
DOI: 10.1111/gbb.12656
PMCID: PMC7507145

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