Genetically predicted breastfeeding propensity and brain microstructural morphology: Insights from genome-wide association study summary statistics and neurogenomics.

doi:10.1016/j.clnesp.2026.103612

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Article

Genetically predicted breastfeeding propensity and brain microstructural morphology: Insights from genome-wide association study summary statistics and neurogenomics.

Clinical nutrition ESPEN - 1 Oct 2026

Peng Wan, Zheng Lu, Huo Fengjing, Gong Huiting, Zhang Ming, Zhu Xiao

Abstract excerpt

BACKGROUND: Breastfeeding provides nutrients and bioactive components relevant to infant development, but observational associations with brain outcomes may be influenced by socioeconomic, maternal, and family-level factors. Mendelian randomization (MR) offers a genetic framework for evaluating associations by using genetic variants as proxies for breastfeeding propensity; it does not directly measure the effect...

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Topics

Humans
Genome-Wide Association Study
Brain
Breast Feeding
Female
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Phenotype

Magnetic Resonance Imaging

UK Biobank

Polymorphism, Single Nucleotide

Male

United Kingdom

Machine Learning

Source

Open in PubMed

Identifiers

PMID: 42501820
DOI: 10.1016/j.clnesp.2026.103612

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