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Article

White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease.

NeuroImage. Clinical - 1 Jan 2014

Adluru Nagesh, Destiche Daniel J, Lu Sharon Yuan-Fu, Doran Samuel T, Birdsill Alex C, Melah Kelsey E, Okonkwo Ozioma C, Alexander Andrew L, Dowling N Maritza, Johnson Sterling C, Sager Mark A, Bendlin Barbara B

Abstract excerpt

INTRODUCTION: Little is still known about the effects of risk factors for Alzheimer's disease (AD) on white matter microstructure in cognitively healthy adults. The purpose of this cross-sectional study was to assess the effect of two well-known risk factors for AD, parental family history and APOE4 genotype. METHODS: This study included 343 participants from the Wisconsin Registry for Alzheimer's Prevention, who...

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Identifiers

PMID: 24936424
DOI: 10.1016/j.nicl.2014.04.008
PMCID: PMC4053649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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