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Article

Hla-C genetic diversity and evolutionary insights in two samples from Brazil and Benin.

HLA - 1 Oct 2020

Souza Andreia S, Sonon Paulin, Paz Michelle A, Tokplonou Léonidas, Lima Thálitta H A, Porto Iane O P, Andrade Heloisa S, Silva Nayane Dos S B, Veiga-Castelli Luciana C, Oliveira Maria Luiza G, Sadissou Ibrahim Abiodoun, Massaro Juliana Doblas, Moutairou Kabirou A, Donadi Eduardo A, Massougbodji Achille, Garcia André, Ibikounlé Moudachirou, Meyer Diogo, Sabbagh Audrey, Mendes-Junior Celso T, Courtin David, Castelli Erick C

Abstract excerpt

Human leukocyte antigen-C (HLA-C) is a classical HLA class I molecule that binds and presents peptides to cytotoxic T lymphocytes in the cell surface. HLA-C has a dual function because it also interacts with Killer-cell immunoglobulin-like receptors (KIR) receptors expressed in natural killer and T cells, modulating their activity. The structure and diversity of the HLA-C regulatory regions, as well as the...

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PMID: 32662221
DOI: 10.1111/tan.13996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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