Article
HLA-F coding and regulatory segments variability determined by massively parallel sequencing procedures in a Brazilian population sample.
Human immunology - 1 Oct 2016
Lima Thálitta Hetamaro Ayala, Buttura Renato Vidal, Donadi Eduardo Antônio, Veiga-Castelli Luciana Caricati, Mendes-Junior Celso Teixeira, Castelli Erick C
Abstract excerpt
Human Leucocyte Antigen F (HLA-F) is a non-classical HLA class I gene distinguished from its classical counterparts by low allelic polymorphism and distinctive expression patterns. Its exact function remains unknown. It is believed that HLA-F has tolerogenic and immune modulatory properties. Currently, there is little information regarding the HLA-F allelic variation among human populations and the available...
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