Article
Genomic characterization of HLA class I and class II genes in ethnically diverse sub-Saharan African populations: A report on novel HLA alleles.
HLA - 1 Aug 2023
Pagkrati Ioanna, Duke Jamie L, Mbunwe Eric, Mosbruger Timothy L, Ferriola Deborah, Wasserman Jenna, Dinou Amalia, Tairis Nikolaos, Damianos Georgios, Kotsopoulou Ioanna, Papaioannou Joanna, Giannopoulos Diamantoula, Beggs William, Nyambo Thomas, Mpoloka Sununguko W, Mokone Gaonyadiwe G, Njamnshi Alfred K, Fokunang Charles, Woldemeskel Dawit, Belay Gurja, Maiers Martin, Tishkoff Sarah A, Monos Dimitri S
Abstract excerpt
HLA allelic variation has been well studied and documented in many parts of the world. However, African populations have been relatively under-represented in studies of HLA variation. We have characterized HLA variation from 489 individuals belonging to 13 ethnically diverse populations from rural communities from the African countries of Botswana, Cameroon, Ethiopia, and Tanzania, known to practice traditional...
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