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Insights into HLA-G Genetics Provided by Worldwide Haplotype Diversity

6 Oct 2014

Abstract excerpt

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I genes, located within the major histocompatibility complex (MHC). HLA-G has been the target of most recent research regarding the function of class I non-classical genes. The main features that distinguish HLA-G from classical class I genes are (a) limited protein variability, (b) alternative splicing generating several membrane...

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PMID: 25339953
DOI: 10.3389/fimmu.2014.00476

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