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Article

Recognition of physiological phosphorylation sites by p21-activated kinase 4.

Journal of structural biology - 1 Sept 2020

Chetty Ashwin K, Sexton Joel A, Ha Byung Hak, Turk Benjamin E, Boggon Titus J

Abstract excerpt

Many serine/threonine protein kinases discriminate between serine and threonine substrates as a filter to control signaling output. Among these, the p21-activated kinase (PAK) group strongly favors phosphorylation of Ser over Thr residues. PAK4, a group II PAK, almost exclusively phosphorylates its substrates on serine residues. The only well documented exception is LIM domain kinase 1 (LIMK1), which is...

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Identifiers

PMID: 32585314
DOI: 10.1016/j.jsb.2020.107553
PMCID: PMC7395882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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