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Article

Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial Fission.

Cardiovascular drugs and therapy - 1 Oct 2020

Lu Zhao-Yang, Qi Jia, Yang Bin, Cao Hui-Li, Wang Rui-Ying, Wang Xuan, Chi Rui-Fang, Guo Chun-Ling, Yang Zhi-Ming, Liu Hui-Min, Li Bao

Abstract excerpt

OBJECTIVE: We have shown previously that diallyl trisulfide (DATS) ameliorates mitochondrial fission and oxidative stress in a hyperglycemia-induced endothelial apoptosis and diabetic mouse model. The aim of this study was to investigate whether DATS mitigates Ang II-induced vascular smooth muscle cell (VSMC) phenotypic switching and vascular remodeling, and if so, to determine the underlying molecular events....

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Identifiers

PMID: 32564303
DOI: 10.1007/s10557-020-07000-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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