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F-53B stimulated vascular smooth muscle cell phenotypic switch and vascular remodeling via ferroptosis-related pathway.

The Science of the total environment - 1 Dec 2024

Zhang Min, Shi Jun, Pan Huichao, Zhu Jie, Wang Xueting, Zhou Jun, Deng Huiping

Abstract excerpt

The compound 6:2 chlorinated polyfluorinated ether sulfonate (F53B), an alternative to perfluorooctane sulfonate (PFOS), has been widely utilized in China. Although the connection between the exposure and toxicity of F53B is established, the role and mechanisms of the compound in promoting vascular remodeling are yet to be elucidated. Thus, the present study investigated the impact of F53B on the function of...

Topics

Ferroptosis
Muscle, Smooth, Vascular
Vascular Remodeling
Animals
Fluorocarbons
Phenotype
Myocytes, Smooth Muscle

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39341237
DOI: 10.1016/j.scitotenv.2024.176565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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