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Article

The Human Leukocyte Antigen Locus and Rheumatic Heart Disease Susceptibility in South Asians and Europeans.

Scientific reports - 2 Jun 2020

Auckland Kathryn, Mittal Balraj, Cairns Benjamin J, Garg Naveen, Kumar Surendra, Mentzer Alexander J, Kado Joseph, Perman Mai Ling, Steer Andrew C, Hill Adrian V S, Parks Tom

Abstract excerpt

Rheumatic heart disease (RHD), an autoinflammatory heart disease, was recently declared a global health priority by the World Health Organization. Here we report a genome-wide association study (GWAS) of RHD susceptibility in 1,163 South Asians (672 cases; 491 controls) recruited in India and Fiji. We analysed directly obtained and imputed genotypes, and followed-up associated loci in 1,459 Europeans (150 cases;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32488134
DOI: 10.1038/s41598-020-65855-8
PMCID: PMC7265443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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