Article
Association of HLA-DRB1*14 with rheumatic heart disease patients from Chandigarh, North India.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Mar 2012
Toor Devinder, Leal Komal, Kumar Rajesh, Sharma Yash Paul, Chakraborti Anuradha
Abstract excerpt
CONTEXT: Acute rheumatic fever (ARF)/rheumatic heart disease (RHD) is a major cause of morbidity and mortality in India, yet, few studies are available on susceptibility markers. OBJECTIVE: To associate human leukocyte antigen (HLA) class II alleles with north Indian RHD patients as genetic susceptibility markers. MATERIALS AND METHODS: HLA alleles were analysed using sequence specific primer-polymerase chain...
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