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Article

"HLA-G 3'UTR gene polymorphisms and rheumatic heart disease: a familial study among South Indian population".

Pediatric rheumatology online journal - 1 Feb 2017

Poomarimuthu Maheshkumar, Elango Sivakumar, Soundrapandian Sambath, Mariakuttikan Jayalakshmi

Abstract excerpt

BACKGROUND: Rheumatic heart disease (RHD) is an autoimmune disease where cross reactive CD4+ T cells are involved in the pathogenesis of valvular damage. Human Leukocyte Antigen-G (HLA-G), an immunosuppressive molecule playing a crucial role in the inhibition of T cell response is associated with the pathogenesis of various autoimmune and inflammatory diseases. Genetic polymorphisms within the 3'untranslated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28143491
DOI: 10.1186/s12969-017-0140-x
PMCID: PMC5286793

Genes

RHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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