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Article

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

Genes and immunity - 1 Sept 2014

Armstrong D L, Zidovetzki R, Alarcón-Riquelme M E, Tsao B P, Criswell L A, Kimberly R P, Harley J B, Sivils K L, Vyse T J, Gaffney P M, Langefeld C D, Jacob C O

Abstract excerpt

In a genome-wide association study (GWAS) of individuals of European ancestry afflicted with systemic lupus erythematosus (SLE) the extensive utilization of imputation, step-wise multiple regression, lasso regularization and increasing study power by utilizing false discovery rate instead of a Bonferroni multiple test correction enabled us to identify 13 novel non-human leukocyte antigen (HLA) genes and confirmed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24871463
DOI: 10.1038/gene.2014.23
PMCID: PMC4156543

Genes

BIN1
CNTN6
EHF
MED1
RASSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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