Article
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.
Annals of the rheumatic diseases - 1 Mar 2015
Kim Kwangwoo, Bang So-Young, Lee Hye-Soon, Cho Soo-Kyung, Choi Chan-Bum, Sung Yoon-Kyoung, Kim Tae-Hwan, Jun Jae-Bum, Yoo Dae Hyun, Kang Young Mo, Kim Seong-Kyu, Suh Chang-Hee, Shim Seung-Cheol, Lee Shin-Seok, Lee Jisoo, Chung Won Tae, Choe Jung-Yoon, Shin Hyoung Doo, Lee Jong-Young, Han Bok-Ghee, Nath Swapan K, Eyre Steve, Bowes John, Pappas Dimitrios A, Kremer Joel M, Gonzalez-Gay Miguel A, Rodriguez-Rodriguez Luis, Ärlestig Lisbeth, Okada Yukinori, Diogo Dorothée, Liao Katherine P, Karlson Elizabeth W, Raychaudhuri Soumya, Rantapää-Dahlqvist Solbritt, Martin Javier, Klareskog Lars, Padyukov Leonid, Gregersen Peter K, Worthington Jane, Greenberg Jeffrey D, Plenge Robert M, Bae Sang-Cheol
Abstract excerpt
OBJECTIVE: A highly polygenic aetiology and high degree of allele-sharing between ancestries have been well elucidated in genetic studies of rheumatoid arthritis. Recently, the high-density genotyping array Immunochip for immune disease loci identified 14 new rheumatoid arthritis risk loci among individuals of European ancestry. Here, we aimed to identify new rheumatoid arthritis risk loci using Korean-specific...
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