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Article

H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect.

Current biology : CB - 22 Jun 2020

Burkhart Kirk B, Sando Steven R, Corrionero Anna, Horvitz H Robert

Abstract excerpt

Maternally inherited RNA and proteins control much of embryonic development. The effect of such maternal information beyond embryonic development is largely unclear. Here, we report that maternal contribution of histone H3.3 assembly complexes can prevent the expression of late-onset anatomical, physiologic, and behavioral abnormalities of C. elegans. We show that mutants lacking hira-1, an evolutionarily...

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Identifiers

PMID: 32470364
DOI: 10.1016/j.cub.2020.04.046
PMCID: PMC7314652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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