Article

Identification of essential genes in <i>Caenorhabditis elegans</i> through whole genome sequencing of legacy mutant collections

2021-06-19

Abstract excerpt

<h4>ABSTRACT</h4> It has been estimated that 15-30% of the ∼20,000 genes in C. elegans are essential, yet many of these genes remain to be identified or characterized. With the goal of identifying unknown essential genes, we performed whole genome sequencing on complementation pairs from legacy collections of maternal-effect lethal and sterile mutants. This approach uncovered maternal genes required for embryoni...

Identifiers and source

Literature Corpus work: c9e33017-37e6-5c5b-85dc-50845017499c
DOI: 10.1101/2021.06.16.448744

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of essential genes in <i>Caenorhabditis elegans</i> through whole genome sequencing of legacy mutant collectionsDOI 10.1101/2021.06.16.448744Read

Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections.Semantic proximity Read

High-throughput capturing and characterization of mutations in essential genes of Caenorhabditis elegans.Semantic proximity Read

Identification of Essential Genes in Caenorhabditis elegans with Lethal Mutations Maintained by Genetic Balancers.Semantic proximity Read

Genomic Identification and Functional Characterization of Essential Genes in Caenorhabditis elegans.Semantic proximity Read

Lethal mutations defining 112 complementation groups in a 4.5 Mb sequenced region of Caenorhabditis elegans chromosome III.Semantic proximity Read

Genetic analysis of sterile mutants in the dpy-5 unc-13 (I) genomic region of Caenorhabditis elegans.Semantic proximity Read

Identification of 315 genes essential for early zebrafish development.Semantic proximity Read

A survey of new temperature-sensitive, embryonic-lethal mutations in C. elegans: 24 alleles of thirteen genes.Semantic proximity Read

Viable maternal-effect mutations that affect the development of the nematode Caenorhabditis elegans.Semantic proximity Read

Dominant maternal-effect mutations causing embryonic lethality in Caenorhabditis elegans.Semantic proximity Read

Mutational accessibility of essential genes on chromosome I(left) in Caenorhabditis elegans.Semantic proximity Read

Combined flow cytometry and high throughput image analysis for the study of essential genes in <i>Caenorhabditis elegans</i>Semantic proximity Read