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Article

Exogenous expression of a histone H3.3 isoform causes extranuclear divisions in the <i>C. elegans</i> intestine

2025-04-14

Abstract excerpt

Histone proteins condense DNA into chromatin and play significant roles in gene regulation. Mutations that alter histone function can disrupt critical gene expression programs and are implicated in driving cancer and other human diseases. Most mechanistic research on histones has been conducted in cell culture, mitotic tissues, or animal disease models rather than in normal tissue. Caenorhabditis elegans is a mod...

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Identifiers and source

Literature Corpus work
c2f43974-2b07-59fa-a868-b58baa04e969
DOI
10.1101/2025.04.10.648275
Open publication

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Exogenous expression of a histone H3.3 isoform causes extranuclear divisions in the <i>C. elegans</i> intestineDOI 10.1101/2025.04.10.648275
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