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Article

Tau accumulates in Crohn's disease gut

21 May 2020

Abstract excerpt

A sizeable body of evidence has recently emerged to suggest that gastrointestinal (GI) inflammation might be involved in the development of Parkinson's disease (PD). There is now strong epidemiological and genetical evidence linking PD to inflammatory bowel diseases and we recently demonstrated that the neuronal protein alpha-synuclein, which is critically involved in PD pathophysiology, is upregulated in...

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PMID: 32436623
DOI: 10.1096/fj.202000414r

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