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Article

Characterization and regulation of alpha-synuclein phosphorylation in enteric neurons under physiological conditions

2025-05-17

Abstract excerpt

Alpha-synuclein is a 140 aa neuronal protein pathologically and genetically linked to Parkinson’s disease (PD). In PD, the major protein modification of alpha-synuclein is phosphorylation at serine 129. Alpha-synuclein is also phosphorylated at low levels under physiological conditions but its regulation and role are still largely unknown. Mounting evidence suggests a role for the gut-brain axis in CNS homeostasis...

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Literature Corpus work
611d5c04-b3a9-545c-86e0-72b3a6ea36e7
DOI
10.22541/au.174745086.62434670/v1
Open publication

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Characterization and regulation of alpha-synuclein phosphorylation in enteric neurons under physiological conditionsDOI 10.22541/au.174745086.62434670/v1
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