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Exogenous Oxytocin Alleviates Prodromal and Clinical Parkinson's Disease Phenotypes via the Inhibition of Enteric Glial Cell-triggered Neuroinflammation

2026-01-07

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<title>Abstract</title> <p> <bold>Background/Aims:</bold> This study aims to elucidate how hyperactivated enteric glial cells (EGCs) trigger Parkinson's disease (PD) pathogenesis and whether the exogenous gut–brain regulatory hormone oxytocin canalleviate the phenotypes of PD. <bold>Methods:</bold> Prodromal and clinical PD mouse models were established via the intragastric administration of rotenone (ROT). T...

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Literature Corpus work
e195a70a-4374-5336-adc8-33a6c87c52ed
DOI
10.21203/rs.3.rs-8516406/v1
Open publication

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Exogenous Oxytocin Alleviates Prodromal and Clinical Parkinson's Disease Phenotypes via the Inhibition of Enteric Glial Cell-triggered NeuroinflammationDOI 10.21203/rs.3.rs-8516406/v1
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