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Exogenous Oxytocin Alleviates Prodromal and Clinical Parkinson's Disease Phenotypes via Inhibiting Enteric Glial Cell triggered Neuroinflammation

2026-01-07

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<title>Abstract</title> <p>Aims This study aims to elucidate how the hyperactivated enteric glial cells (EGCs) trigger Parkinson's Disease (PD) pathogenesis and if exogenous gut-brain regulatory hormone oxytocin could alleviate the phenotypes of PD. Methods Prodromal and clinical PD mice model were established via intragastric administration of rotenone (ROT). Intestinal and motor function of the mice were asse...

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Literature Corpus work
dedc7959-d65b-508d-b4f2-c5ae4db856ca
DOI
10.21203/rs.3.rs-8512158/v1
Open publication

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Exogenous Oxytocin Alleviates Prodromal and Clinical Parkinson's Disease Phenotypes via Inhibiting Enteric Glial Cell triggered NeuroinflammationDOI 10.21203/rs.3.rs-8512158/v1
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