Article

Intragastric administration of low-dose rotenone post-colitis exacerbates damage to the nigrostriatal dopaminergic system in Parkinson’s disease: The pace accelerates even more

2022-12-22

Abstract excerpt

<h4>Background</h4> The contribution of gastrointestinal (GI) inflammation and local exposure to neurotoxins in the gut offers the most in-depth explanation of Parkinson’s disease (PD) etiopathogenesis through abnormal accumulation and spreading of alpha-synuclein (α-syn) aggregates from the gut to the brain. <h4>Objectives</h4> This study was designed to investigate whether dextran sodium sulfate (DSS)-mediated...

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Literature Corpus work: d583cdef-162b-5046-8ff3-c13d0495c115
DOI: 10.1101/2022.12.22.521569

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Intragastric administration of low-dose rotenone post-colitis exacerbates damage to the nigrostriatal dopaminergic system in Parkinson’s disease: The pace accelerates even moreDOI 10.1101/2022.12.22.521569Read

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