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Article

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy

20 Feb 2017

Abstract excerpt

BACKGROUND: Recent evidence suggests that Parkinson's disease (PD) is associated with intestinal microbiota dysbiosis, abnormal intestinal permeability, and intestinal inflammation. OBJECTIVE: Our study aimed to determine if these gut abnormalities are present in another synucleinopathy, multiple system atrophy (MSA). METHODS: In six MSA and 11 healthy control subjects, we performed immunohistochemistry studies...

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PMID: 28234259
DOI: 10.3233/jpd-160991

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