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Article

Comparing Phylogenetic Approaches to Reconstructing Cell Lineage From Microsatellites With Missing Data.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Lyne Anne-Marie, Perie Leila

Abstract excerpt

Due to the imperfect fidelity of DNA replication, somatic cells acquire DNA mutations at each division which record their lineage history. Microsatellites, tandem repeats of DNA nucleotide motifs, mutate more frequently than other genomic regions and by observing microsatellite lengths in single cells and implementing suitable inference procedures, the cell lineage tree of an organism can be reconstructed. Due to...

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PMID: 32386163
DOI: 10.1109/TCBB.2020.2992813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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