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Article

Gene expression differences among different MSI statuses in colorectal cancer.

International journal of cancer - 1 Oct 2018

Chen Lei, Pan Xiaoyong, Hu XiaoHua, Zhang Yu-Hang, Wang ShaoPeng, Huang Tao, Cai Yu-Dong

Abstract excerpt

Colorectal cancer is the third most common cancer in males and second in females. This disease can be caused by genetic and acquired/environmental factors. Microsatellite instability (MSI) is one of the major mechanisms in colorectal cancer. This mechanism is a specific condition of genetic hyper mutability that results from incompetent DNA mismatch repair. MSI has been applied to classify different colorectal...

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Algorithms
Biomarkers, Tumor
Colorectal Neoplasms
Gene Expression Profiling
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Machine Learning

Microsatellite Instability

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PMID: 29696646
DOI: 10.1002/ijc.31554

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