Article
Gene expression differences among different MSI statuses in colorectal cancer.
International journal of cancer - 1 Oct 2018
Chen Lei, Pan Xiaoyong, Hu XiaoHua, Zhang Yu-Hang, Wang ShaoPeng, Huang Tao, Cai Yu-Dong
Abstract excerpt
Colorectal cancer is the third most common cancer in males and second in females. This disease can be caused by genetic and acquired/environmental factors. Microsatellite instability (MSI) is one of the major mechanisms in colorectal cancer. This mechanism is a specific condition of genetic hyper mutability that results from incompetent DNA mismatch repair. MSI has been applied to classify different colorectal...
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