Article
The Metabolization Profile of the CYP2D6 Gene in Amerindian Populations: A Review.
Genes - 28 Feb 2020
Leitão Luciana P C, Souza Tatiane P, Rodrigues Juliana C G, Fernandes Marianne R, Santos Sidney, Santos Ney P C
Abstract excerpt
BACKGROUND: the CYP2D6 gene is clinically important and is known to have a number of variants. This gene has four distinct metabolization profiles that are determined by the different allelic forms present in the individual. The relative frequency of these profiles varies considerably among human populations around the world. Populations from more isolated regions, such as Native Americans, are still relatively...
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