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Article

CYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?

Omics : a journal of integrative biology - 1 Sept 2017

de Andrés Fernando, Sosa-Macías Martha, Ramos Blanca Patricia Lazalde, Naranjo María-Eugenia G, LLerena Adrián

Abstract excerpt

Global precision medicine demands characterization of drug metabolism and phenotype variation in diverse populations, including the indigenous societies. A related question is the extent to which CYP450 drug metabolizing enzyme genotype and phenotype data are concordant and whether they can be used interchangeably. These issues are increasingly debated as precision medicine continues to expand as a popular...

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PMID: 28873029
DOI: 10.1089/omi.2017.0101

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