Article
Worldwide interethnic variability and geographical distribution of CYP2C9 genotypes and phenotypes.
Expert opinion on drug metabolism & toxicology - 1 Jan 2015
Céspedes-Garro Carolina, Fricke-Galindo Ingrid, Naranjo María Eugenia G, Rodrigues-Soares Fernanda, Fariñas Humberto, de Andrés Fernando, López-López Marisol, Peñas-Lledó Eva M, LLerena Adrián
Abstract excerpt
INTRODUCTION: Notably differences in CYP2C9 allele frequencies among worldwide populations have been reported, with an interesting low frequency of the CYP2C9*2 allele in Amerindians compared with Admixed and European populations. AREAS COVERED: Literature was searched using the PubMed database and was focused on worldwide original research papers on CYP2C9 alleles and CYP2C9 phenotypes ("predicted" from CYP2C9...
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