Article
Pharmacogenetics in Central American healthy volunteers: interethnic variability.
Drug metabolism and personalized therapy - 1 Mar 2015
Céspedes-Garro Carolina, Naranjo María-Eugenia G, Ramírez Ronald, Serrano Víctor, Fariñas Humberto, Barrantes Ramiro, LLerena Adrián
Abstract excerpt
Ethnicity is one of the major factors involved in interindividual variability to drug response. This study aims to describe the frequency of the most relevant pharmacogenetic biomarkers and metabolic phenotypes in Central American healthy volunteers and to determine its interethnic variability. Twenty-six original research articles on allelic, genotypes or metabolic phenotype frequencies were analyzed, in which a...
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