Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of ADME-related genes and their implications for drug safety and efficacy in Amazonian Amerindians

10 May 2019

Abstract excerpt

The variation in the allelic frequencies of polymorphic pharmacogenes among different ethnic groups may be responsible for severe adverse reactions to or altered efficacy of a wide variety of drugs. Amazonian Amerindian populations have a unique genetic profile that may have a fundamental on the efficacy and safety of certain drugs. The genetic characteristics of these populations are poorly known, which can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Genomics and Rare Diseases
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31076604
DOI: 10.1038/s41598-019-43610-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of ADME-related genes and their implications for drug safety and efficacy in Amazonian AmerindiansPMID 31076604Read ↗

The need to diversify genomic studies: Insights from Andean highlanders and Amazonians.Semantic proximity Read ↗

Pharmacogenomic implications of population admixture: Brazil as a model case.Semantic proximity Read ↗

Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters.Semantic proximity Read ↗

Population Diversity in Pharmacogenetics: A Latin American Perspective.Semantic proximity Read ↗

Increased genetic diversity of ADME genes in African Americans compared with their putative ancestral source populations and implications for pharmacogenomics.Semantic proximity Read ↗

Polymorphisms in genes involved in the absorption, distribution, metabolism, and excretion of drugs in the Kazakhs of Kazakhstan.Semantic proximity Read ↗

Opportunities and Challenges of Population PharmacogenomicsSemantic proximity Read ↗

Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public healthSemantic proximity Read ↗

Global patterns of genetic diversity and signals of natural selection for human ADME genes.Semantic proximity Read ↗

Pharmacogenomics in the Americas: the impact of genetic admixture.Semantic proximity Read ↗

The Metabolization Profile of the CYP2D6 Gene in Amerindian Populations: A Review.Semantic proximity Read ↗

Genetic diversity of variants involved in drug response among Tunisian and Italian populations toward personalized medicine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.