Article
CYP2D6 in Amerindians from Southern Mexico: low variability and higher frequency of functional alleles.
Drug metabolism and personalized therapy - 1 Dec 2015
Perez-Paramo Yadira X, Hernandez-Cabrera Francisco, Rojas-Martinez Augusto, Ortiz-Lopez Rocio
Abstract excerpt
BACKGROUND: Several functional and nonfunctional CYP2D6 variants have been associated with interindividual and interethnic variability in pharmacological responses. The aim of this article was to study the diversity and the interpopulation relationships of CYP2D6 variants of south Native Mexicans to define predicted phenotypes. CONTENTS: A fully systematic review of CYP2D6 variants reported in Amerindian...
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