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Article

Effects of gene mutation and disease progression on representative neural circuits in familial Alzheimer's disease.

Alzheimer's research & therapy - 14 Jan 2020

Quan Meina, Zhao Tan, Tang Yi, Luo Ping, Wang Wei, Qin Qi, Li Tingting, Wang Qigeng, Fang Jiliang, Jia Jianping

Abstract excerpt

BACKGROUND: Although structural and functional changes of the striatum and hippocampus are present in familial Alzheimer's disease, little is known about the effects of specific gene mutation or disease progression on their related neural circuits. This study was to evaluate the effects of known pathogenic gene mutation and disease progression on the striatum- and hippocampus-related neural circuits, including...

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Identifiers

PMID: 31937364
DOI: 10.1186/s13195-019-0572-2
PMCID: PMC6961388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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