Article
Genetic and Epigenetic Analysis Revealing Variants in the NCAM1-TTC12-ANKK1-DRD2 Cluster Associated Significantly With Nicotine Dependence in Chinese Han Smokers.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 16 Jul 2020
Liu Qiang, Xu Yi, Mao Ying, Ma Yunlong, Wang Maiqiu, Han Haijun, Cui Wenyan, Yuan Wenji, Payne Thomas J, Xu Yizhou, Li Ming D, Yang Zhongli
Abstract excerpt
BACKGROUNDS: Although studies have demonstrated that the NCAM1-TTC12-ANKK1-DRD2 gene cluster plays essential roles in addictions in subjects of European and African origin, study of Chinese Han subjects is limited. Further, the underlying biological mechanisms of detected associations are largely unknown. METHODS: Sixty-four single-nucleotide polymorphisms (SNPs) in this cluster were analyzed for association with...
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