Article
Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population.
Scientific reports - 29 Aug 2017
Wen Li, Han Haijun, Liu Qiang, Su Kunkai, Yang Zhongli, Cui Wenyan, Yuan Wenji, Ma Yunlong, Fan Rongli, Chen Jiali, Jiang Keran, Jiang Xianzhong, Payne Thomas J, Wang Jundong, Li Ming D
Abstract excerpt
Although numerous studies have revealed significant associations between variants in the nicotinic acetylcholine receptors (nAChR) subunits and nicotine dependence (ND), only few studies were performed in Chinese subjects. Here, we performed association and interaction analysis for 20 single nucleotide polymorphisms (SNPs) in the CHRNB3-CHRNA6 gene cluster with ND in a Chinese Han population (N = 5,055). We found...
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