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Article

Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2009

Huang Weihua, Payne Thomas J, Ma Jennie Z, Beuten Joke, Dupont Randolph T, Inohara Naohiro, Li Ming D

Abstract excerpt

The dopaminergic system in the brain plays a critical role in nicotine addiction. Genetic variants in the dopaminergic system, including those in dopamine receptor genes, represent plausible candidates for the genetic study of nicotine dependence (ND). We investigated various polymorphisms in the dopamine D(2) receptor gene (DRD2) and its neighboring ankyrin repeats and kinase domain containing 1 gene (ANKK1) to...

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Source

Identifiers

PMID: 18354387
DOI: 10.1038/npp.2008.37

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample.PMID 18354387Read ↗

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