Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples.

Human molecular genetics - 1 Dec 2007

Yang Bao-Zhu, Kranzler Henry R, Zhao Hongyu, Gruen Jeffrey R, Luo Xingguang, Gelernter Joel

Abstract excerpt

There have been many conflicting reports concerning the association of the DRD2 locus with alcohol dependence (AD). To investigate whether these findings could be reconciled by considering the genomic region of DRD2 in greater detail, we conducted two separate association studies of AD in 1220 European-American subjects using family-based (488 subjects) and case-control (318 cases and 414 controls) designs, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to CD56 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

Share to Family

Share to Multigene Family

Share to Neural Cell Adhesion Molecules

Share to Protein Serine-Threonine Kinases

Share to Receptors, Dopamine D2

Source

Identifiers

PMID: 17761687
DOI: 10.1093/hmg/ddm240

Genes

DRD2
NCAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples.PMID 17761687Read ↗

Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence.Semantic proximity Read ↗

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations.Semantic proximity Read ↗

Genetic and Epigenetic Analysis Revealing Variants in the NCAM1-TTC12-ANKK1-DRD2 Cluster Associated Significantly With Nicotine Dependence in Chinese Han Smokers.Semantic proximity Read ↗

Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study.Semantic proximity Read ↗

Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.Semantic proximity Read ↗

Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions.Semantic proximity Read ↗

ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Semantic proximity Read ↗

DRD2 and ANKK1 gene polymorphisms and alcohol dependence: a case-control study among a Mendelian population of East Asian ancestry.Semantic proximity Read ↗

A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response.Semantic proximity Read ↗

Ankyrin Repeat and Kinase Domain Containing 1 Gene, and Addiction Vulnerability.Semantic proximity Read ↗

Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample.Semantic proximity Read ↗

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.