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Article

Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes.

Scientific reports - 6 Feb 2017

Xu Hongqin, Wang Fan, Kranzler Henry R, Gelernter Joel, Zhang Huiping

Abstract excerpt

Altered DNA methylation in addiction-related genes may modify the susceptibility to alcohol or drug dependence (AD or ND). We profiled peripheral blood DNA methylation levels of 384 CpGs in promoter regions of 82 addiction-related genes in 256 African Americans (AAs) (117 cases with AD-ND codependence and 139 controls) and 196 European Americans (103 cases with AD-ND codependence and 93 controls) using Illumina's...

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Identifiers

PMID: 28165486
DOI: 10.1038/srep41816
PMCID: PMC5292964

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