Article
Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population.
Translational psychiatry - 18 Apr 2018
Liu Qiang, Han Haijun, Wang Maiqiu, Yao Yinghao, Wen Li, Jiang Keran, Ma Yunlong, Fan Rongli, Chen Jiali, Su Kunkai, Yang Zhongli, Cui Wenyan, Yuan Wenji, Jiang Xianzhong, Li Jingjing, Payne Thomas J, Wang Jundong, Li Ming D
Abstract excerpt
Nicotine dependence (ND) is a worldwide health problem. Numerous genetic studies have demonstrated a significant association of variants in nicotinic acetylcholine receptors (nAChRs) with smoking behaviors. However, most of these studies enrolled only subjects of European or African ancestry. In addition, although an increasing body of evidence implies a causal connection of single-nucleotide polymorphisms (SNPs)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.