Article
The genetic variability of hepatitis B virus subgenotype F1b precore/core gene is related to the outcome of the acute infection.
Virus research - 1 Feb 2020
Trinks Julieta, Marciano Sebastián, Esposito Isabella, Franco Alejandra, Mascardi Maria Florencia, Mendizabal Manuel, Livellara Beatriz, Arrigo Diego, Calzetta Pablo, Vujacich Claudia, Giunta Diego, Gadano Adrián, Flichman Diego
Abstract excerpt
AIM: To assess the association of viral and host genetic variability with the outcome of acute infection with hepatitis B virus subgenotype F1b (HBV/F1b). METHODS: The cohort consisted of 26 patients with acute HBV/F1b infection who exhibit different outcomes: spontaneous resolution (n = 10), progression to chronic hepatitis (n = 10) and acute liver failure (n = 6). HLA SNPs (rs3077, rs9277542, rs2856718 and...
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