Article
Different mutation rates in the basal core promoter and precore regions between hepatitis B virus subgenotype F1b clusters.
Journal of viral hepatitis - 1 Jun 2023
Martínez Micaela, Elizalde María Mercedes, Giadans Cecilia Graciela, Monzani Cecilia, Campos Rodolfo, Flichman Diego
Abstract excerpt
Hepatitis B virus (HBV) is the main etiological agent of hepatocellular carcinoma (HCC) worldwide. It has been classified into nine genotypes and several subgenotypes, with uneven global distribution. There is growing evidence that the viral genotype influences the course and outcome of chronic hepatitis B infection. Two evolutionarily different clusters of the subgenotype F1b, called basal and cosmopolitan, have...
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