Article
The variability of hepatitis B envelope is associated with HBs antigen persistence in either chronic or acute HBV genotype A infection.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Sept 2017
Eschlimann Marine, Malvé Brice, Velay Aurélie, Fenaux Honorine, Berger Sibel, Frippiat Jean-Pol, Zoulim Fabien, Bensenane Mouni, Bronowicki Jean-Pierre, Goehringer François, May Thierry, Jeulin Hélène, Schvoerer Evelyne
Abstract excerpt
BACKGROUND: More than 240 million people are chronically infected by hepatitis B virus (HBV) worldwide. Envelope proteins play a crucial role in viral cellular entry and immune recognition. The loss of HBs antigen (HBsAg) correlated with a good clinical prognosis is rarely achieved with or without treatment (3-16%). OBJECTIVES: HBV envelope variability was investigated according to HBsAg persistence. STUDY...
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