Article
Characterization of Full-Length Genomes of Hepatitis B Virus Quasispecies in Sera of Patients at Different Phases of Infection.
Journal of clinical microbiology - 1 Jul 2015
Yang Zhi-Tao, Huang Su-Yuan, Chen Li, Liu Feng, Cai Xiao-Hui, Guo Yang-Fan, Wang Ming-Jie, Han Yue, Yu De-Min, Jiang Jie-Hong, Zhang Dong-Hua, Gong Qi-Ming, Zhang Guo-Qing, Zang Guo-Qing, Lu Zhong-Hua, Huang Li-Hua, Zhang Xin-Xin
Abstract excerpt
Hepatitis B virus (HBV) infection results in different clinical presentation due to different levels of immune response. Our study aimed to characterize HBV full-length genome quasispecies (QS) in patients with different phases of infection to better understand its pathogenesis. Forty treatment-naive HBV-infected patients were enrolled, including 10 cases of acute hepatitis B (AHB), 9 cases of immunotolerant (IT)...
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