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Article

Genome-wide characterisation of hepatitis B mutations involved in clinical outcome.

Heredity - 1 Dec 2006

Szmaragd C, Foster G R, Manica A, Bartholomeusz A, Nichols R A, Balloux F

Abstract excerpt

Infection with the hepatitis B virus (HBV) leads to different disease outcomes, which can be broadly divided into three categories: acute mild infection, 'fulminant' and chronic hepatitis (long-term persistent form of the infection). The factors that influence the development of these different disease states are poorly understood and may include viral polymorphisms. To investigate this possibility, we analysed...

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PMID: 16896341
DOI: 10.1038/sj.hdy.6800882

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